The Differential Effect of Khat (Catha Edulis) Celestraceae and its Potent Alkaloids on the Release of Dopamine Using an In Vitro Model
Dec 22, 2010 · Catha edulis (khat) is a plant grown commonly in the horn of Africa. The leaves of khat are chewed by the people for its stimulant action. Its young buds and tender leaves are chewed to attain a state of euphoria and stimulation. Khat is an evergreen shrub, which is cultivated as a bush or small tree. The leaves have an aromatic odor.
34th ECDD 2006/4.4 khat Assessment of khat (Catha edulis Forsk) 1.
of aqueous extract (450mg/kg) of Catha edulis in diabetic and normal rats caused reduction in body weight from 304.81±14.46 to 237.37±12.28 (22.1%) (p<0.01) Results of present study showed that oral administration of crude extract of Catha edulis exert a hypoglycemic effect in normal and STZ induced type 2 diabetic rats.
ALKALOIDS OF KHAT ( C A T H A EDULIS) 145 action (13,27,29-33);indeed, there is cross-tolerance between the two (34).The alkaloid acts by facilitating release at physiological catecholamine storage sites (30,31)and is viewed as the major source of the symptoms of khat chewing (32).
Catha edulis Celastraceae or Khat (as it’s commonly known) is a popular plant which is chewed for its stimulating effect as a social drug amongst societies in Eastern Africa and Southern Arabia.
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Overview Information Khat is a plant. The leaf and stem are used as a recreational drug and as medicine. As a recreational drug, the leaves and stem are chewed by people in East Africa and the